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Children in polluted cities at increased risk of Alzheimer's, reveals study

The findings indicated that Alzheimer's starts in early childhood

Press Trust of India  |  Washington 

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Children and young adults living in polluted megacities are at significantly increased risk of developing Alzheimer's, a study has found.

Researchers at the in the US studied 203 autopsies of residents ranging in age from 11 months to 40 years.

For the study, published in the Journal of Environmental Research, they tracked two abnormal proteins that indicate development of Alzheimer's, and detected the early stages of the in babies less than a year old.

"Alzheimer's hallmarks start in childhood in polluted environments, and we must implement effective preventative measures early," said Calderon-Garciduenas from the

The researchers found heightened levels of the two abnormal proteins - hyperphosphorylated tau and beta amyloid - in the brains of young urbanites with lifetime exposures to fine-particulate-matter pollution (PM2.5).

They also tracked Apolipoprotein E (APOE 4), a well-known genetic risk factor for Alzheimer's, as well as lifetime cumulative exposure to unhealthy levels of PM2.5 - particles which are at least 30 times smaller than the diameter of a human hair and frequently cause the haze over urban areas.

The findings indicated that Alzheimer's starts in early childhood.

The researchers found hallmarks of the among 99.5 per cent of the subjects they examined in

First Published: Sat, April 14 2018. 22:41 IST
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