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Immunotheraphy may be safe for treating diabetes, retrain immune system

Due to this trial, lesser insulin is needed to control people's blood glucose levels

IANS  |  London 

sugar, diabetes, injection
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Scientists have in a clinical trial found that immunotherapy, which enhances metabolic effects, can be a safe treatment method for patients with

Researchers from King's College London and Cardiff University found that using a peptide technology may potentially help to "retrain" the and thus slow the progression of diabetes.

"It was encouraging to see that people who receive the treatment needed less to control their blood glucose levels, suggesting that their was working better," said Colin Dayan, Professor at the Cardiff University in the UK.

develops when a patient's mistakenly attacks the insulin-producing beta cells in the

Without treatment the number of beta cells slowly decrease and the body no longer is able to maintain (blood glucose) levels.

In the trial, published in the journal Science Translational Medicine, when the diabetic patients were injected with -- small fragments of protein molecules found in beta cells of -- they demonstrated noticeable changes in their immune systems' behaviour.

"The peptide technology used in our trial not only appears to be safe for patients at this stage, but it also has a noticeable effect on the immune system," explained lead researcher Mark Peakman, Professor at King's College London.

There is currently no cure for Type-1 diabetes, which can affect major organs in the body, including heart, blood vessels, nerves, and

"These new findings are an exciting step towards immunotherapies being used to prevent this serious condition from developing in those at high risk, or stop it from progressing in those already diagnosed," said Elizabeth Robertson, Director at the Diabetes UK -- a charity organisation.

First Published: Thu, August 10 2017. 21:00 IST
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