The Wafa news agency reported that Israeli forces closed the Huwwara checkpoint after an Israeli settler was shot dead on Tuesday night.
Meanwhile, the Israeli forces carried out more raids in Nablus and other nearby villages, in response to Tuesday's shooting.
Since then, Israeli forces have killed 12 Palestinians. Unofficial figures of casualties vary between 30 to 40.
At least 2,900 others have been injured and more than 400 arrested so far.
Jerusalem is considered as a sacred place and is home to Jewish, Christian and Muslim holy sites. However, it is also a disputed territory, contested by both Israel and Palestine, which sees it as the capital of its future state.
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