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Limiting the intake of foods rich in asparagine including dairy, beef, poultry, eggs, fish, nuts, soy and whole grains, while increasing the intake of fruits and vegetables may potentially help halt the spread of a deadly type of breast cancer, researchers, including one of Indian-origin, suggests.
Asparagine is an amino acid -- the building blocks that cells use to make proteins.
"Our study adds to a growing body of evidence that suggests diet can influence the course of the disease," said lead authpr Simon Knott, Associate Director at the Cedars-Sinai Medical Centre -- a US-based non-profit.
"This study may have implications not only for breast cancer, but for many metastatic cancers," added Ravi Thadhani, from the varsity.
In the study, published in the journal Nature, the team discovered that the appearance of asparagine synthetase -- the enzyme cells used to make asparagine -- in a primary tumour was strongly associated with later cancer spread.
"The study suggests that changes in diet might impact both how an individual responds to primary therapy and their chances of lethal disease spreading later in life," said Gregory J. Hannon, professor at the University of Cambridge in England.
Researchers are now considering conducting an early-phase clinical trial in which healthy participants would consume a low-asparagine diet.
If the findings are confirmed in human cells, limiting the amount of asparagine cancer patients ingest could be a potential strategy to augment existing therapies and to prevent the spread of breast cancer, Knott added.
(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)