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Hundreds of passengers flying out of London's Heathrow did so on Thursday without their luggage after the airport's baggage system failed, the BBC reported.
The problem affected British Airways, Iberia and American Airlines flights in Terminal 3 and Terminal 5.
Heathrow said the problem had now been fixed and apologised.
It said passengers forced to travel without their luggage should contact their airline to find out when it would be returned to them.
Although flights were able to operate as normal, it is understood that hundreds of passengers departed without their bags.
People were advised to pack essential items in their hand luggage.
The baggage problem comes three weeks after an IT system failure caused chaos for thousands of British Airways passengers.