The Uruguayan Football Association (AUF) postponed four of the five matches scheduled in the Primera Division due to heavy storms.
Three of the fixtures -- River Plate-Nacional, Cerro-Sud America and Racing-Boston River -- were in the capital, which was lashed by heavy rain and gale-force winds on Saturday night and Sunday, reports Xinhua news agency.
The other match rescheduled was Plaza Colonia's clash with Fenix in Colonia de Sacramento.
In a statement, the AUF said the matches would be played on Tuesday.
Penarol currently lead the 16-team Clausura tournament, with four wins from as many matches.