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Vitamin D may cut heart failure risk after heart attack

IANS  |  Sydney 

Besides helping build strong bones and muscles, D may also protect tissue and prevent failure after a attack, finds a study conducted on mice.

failure is a life-threatening condition affecting an estimated 23 million people worldwide.

D prevents excessive scarring and thickening of tissue following a attack, which may help reduce the risk of failure.

"This is a problem because scarring of tissue can reduce the heart's ability to pump blood effectively, which can lead to failure," said James Chong, at the for Medical Research in Australia.

For the study, published in the journal Lung and Circulation, researchers used mouse models to investigate the impact of 1,25D -- a form of D that interacts with hormones -- on the cardiac colony-forming unit fibroblasts (cCFU-Fs)cells that form tissue after a attack.

attacks occur when blood supply to the is blocked, leading to tissue damage. This triggers an where the cCFU-Fs replace the damaged tissue with collagen-based tissue.

"Our research shows that D actually blocks the cCFU-Fs from forming tissue. By blocking cCFU-Fs, D may play an important role in lowering the risk of failure after a attack," Chong said.

"The benefits of D are becoming increasingly known, but we still don't fully understand how mechanistically it can help with disease management. We wanted to know more about how D protects the after a attack," he added.



(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Fri, March 09 2018. 18:30 IST