The ministry said the Mi-8 helicopter went down Monday near the village of Alexandrovka in the Tomsk region, about 3,000 kms east of Moscow.
It was carrying a patient to a local hospital when it crashed.
Officials wouldn't identify the cause of the crash pending official probe.
A day earlier, an An-148 passenger plane operated by a Russian regional carrier went down minutes after takeoff from Moscow, killing all 71 people on board.
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