The 36-year-old actress, who was recently seen in two films, "Snow White and the Huntsman" and "Prometheus", said that the idea of starring in a Broadway or West End play terrifies her, reported Digital Spy online.
"I'm just not made for that kind of live audience where you don't create a fourth wall. I take my hat off to those guys. It's not disconnected enough for me. Some people are good at performing in front of people like that, but I'm uncomfortable with it," Theron said.
The actress turned down an offer from "Young Adult" director Jason Reitman to take part in his theatrical readings at the Los Angeles County Museum of Art.
"I've even said to Jason, 'I will jump off a building for you, but I will not do that'," she added.