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In his first nomination in the category, Guillermo del Toro took home the Golden Globe for Best Director for "The Shape of Water" and thanked monsters for being the patron saints of "our blissful imperfections".
His win has cemented the film's chances at the Oscars this year.
The movie, which entered the race with maximum seven nominations, is a lyrical drama of a mute cleaning lady at a government lab and her unique bond with a mysterious scaled creature, living in the lab's water tank. The creature is a classified secret.
The 53-year-old Mexican filmmaker, known for alternating between dark Spanish language pieces and American mainstream films, described how "monsters" shaped his personality since childhood.
"Since childhood I've been faithful to monsters. I've been saved and absolved by them because monsters are the patron saints of our blissful imperfections and they allow and embody the possibility of fail(ure) and live.
"For 25 years, I have hand-crafted very strange little tales, made of motion, colour, light and shadow," he said in his acceptance speech.
"These strange stories and fables have saved my life. Once with 'The Devil's Backbone' and then with 'Pan's Labyrinth' and now with 'The Shape of Water'."
He also told off the producers in Hollywood for trying to play him off.
He was also nominated in the category of Best Screenplay of a Motion Picture. del Toro lost to Martin McDonagh, who also received the nomination for Best Director for Motion Picture, for his work in "Three Billboards".
Directors Patty Jenkins of "Wonder Woman", Greta Gerwig of "Lady Bird" and Dee Rees of "Mudbound" were not the part of the final five though they directed some of the best movies last year.
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