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Menopausal hormone therapy may reduce heart failure risk: study

Press Trust of India  |  London 

Scientists, including one of Indian origin, have found that menopausal (MHT) may lower risk of

"This is the first study to look at the relationship between the use of menopausal and subtle changes in the structure and function of the heart, which can be predictors of future heart problems," said Mihir Sanghvi from Mary


For the study, published in the journal PLOS ONE, the researchers examined the left ventricular (LV) and left atrial (LA) structure and function in 1,604 post-menopausal women, who were free of known cardiovascular disease, and 32 per cent of whom had used for at least three years.

They found that use was not associated with adverse changes in cardiac structure and function.

Indeed, significantly smaller LV and LA chamber volumes were observed, which have been linked to favourable cardiovascular outcomes, including lower mortality and risk of heart failure, in other settings.

They also looked at LV mass - one of the most important characteristics observed in cardiovascular imaging, with increases in LV mass predicting a higher incidence of cardiovascular events and mortality.

Importantly, they found no significant difference in LV mass between the two groups of women.

"For most menopausal women - especially those under the age of 60 - the benefits of taking outweigh any potential risks. However, each woman's situation is different so please speak to your GP about whether is appropriate for you," Sanghvi said.

"However, women should not take specifically to improve their heart health, as this study does not consider all of the ways this therapy affects our cardiovascular health," researchers said.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Fri, March 09 2018. 16:45 IST
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