The Duke and Duchess of Cambridge will spend Christmas at the Middleton home in Bucklebury, Berkshire rather than with the Queen at Sandringham, a Clarence House spokesman said.
The decision has been taken with the approval of the Queen.
The couple, both 30, are also planning a visit to the Sandringham Estate, in Norfolk, during the festive period.
They spent last Christmas there with other members of the Royal Family when the Queen's husband, Prince Philip was in hospital after undergoing a heart procedure.
The decision to spend this Christmas Day with the Middleton family was taken before it was announced that Kate was pregnant, the BBC reported.
Earlier this month the duchess spent three days in hospital after suffering severe morning sickness, hyperemesis gravidarum, which leaves expectant mothers unable to keep food or liquids down.
She was then ordered by doctors to have a period of rest at home at Kensington Palace.
Kate's parents, who run a party supplies business, and her sister Pippa and brother James are expected to be spending Christmas with the royal couple.