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Taking paracetamol during pregnancy linked to language delay

Press Trust of India  |  New York 

Scientists have found an elevated rate of in girls at 30 months old born to mothers who used (also known as paracetamol) during is the active ingredient in Tylenol and hundreds of over-the-counter and prescription medicines.

It is commonly prescribed during to relieve and This is the first study to examine language development in relation to levels in urine. Information was gathered from 754 women who were enrolled into the study in weeks 8-13 of their Researchers at Icahn School of at in the US asked participants to report the number of tablets they had taken between conception and enrolment, and tested the concentration in their urine at enrolment. The frequency of language delay, defined as the use of fewer than 50 words, was measured by both a nurse's assessment and a follow-up questionnaire filled out by participants about their child's language milestones at 30 months. was used by 59 per cent of the women in early pregnancy, according to the study published in the journal European Psychiatry. use was quantified in two ways: High use vs no use analysis used women who did not report any use as the comparison group. For the urine analysis, the top quartile of exposure was compared to the lowest quartile. was seen in 10 percent of all the children in the study, with greater delays in boys than girls overall. However, girls born to mothers with higher exposure - those who took more than six times in early - were nearly six times more likely to have language delay than girls born to mothers who did not take These results are consistent with studies reporting decreased IQ and increased communication problems in children born to mothers who used more during Both the number of tablets and concentration in urine were associated with a significant increase in in girls, and a slight but not significant decrease in boys. Overall, the results suggest that use in results in a loss of the well-recognised female advantage in language development in early childhood. "Given the prevalence of prenatal use and the importance of language development, our findings, if replicated, suggest that pregnant women should limit their use of this analgesic during pregnancy," said Shanna Swan, from the Icahn School of at

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

First Published: Sat, January 13 2018. 14:25 IST