You are here: Home » PTI Stories » National » News
Business Standard

UK scientists discover hormone to curb alcohol cravings

Press Trust of India  |  London 

Scientists in the have discovered a liver hormone which plays a crucial role in controlling the drinking limits of the body.

The discovery of FGF21, reported in the 'Proceedings in the National Academy of Sciences' journal this week, could lead to a pill that could help alcoholics curb their cravings for alcohol.



Professor Gunter Schumann, from the Institute of Psychiatry at said: "Our study reveals a previously unrecognised liver-brain pathway which regulates alcohol consumption in humans, and which could one day be targeted therapeutically to suppress consumption in problem drinkers".

"The point towards an intriguing feedback loop, where FGF21 is produced in the liver in response to sugar and alcohol intake, which then acts directly on the brain to limit consumption. We cannot rule out the possibility that beta-Klotho acts by affecting neighbouring genes, so further genetic studies are warranted," Schumann said.

samples were analysed from more than 105,000 people of European descent, who were also questioned about their weekly drinking habits.

Although the effect that the gene had was small, the possible mechanism involved may lead to a target for drugs to help people to cut down on their drinking.

Co-author Professor Paul Elliott, from Imperial College London, said: "Our findings may eventually lead to new treatments for people whose health is being harmed by drinking."

By looking at the genomes of the research sample, researchers found that even moderate drinking was increased by gene mutation.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

RECOMMENDED FOR YOU

UK scientists discover hormone to curb alcohol cravings

Scientists in the UK have discovered a liver hormone which plays a crucial role in controlling the drinking limits of the body. The discovery of FGF21, reported in the 'Proceedings in the National Academy of Sciences' journal this week, could lead to a pill that could help alcoholics curb their cravings for alcohol. Professor Gunter Schumann, from the Institute of Psychiatry at King's College London said: "Our study reveals a previously unrecognised liver-brain pathway which regulates alcohol consumption in humans, and which could one day be targeted therapeutically to suppress consumption in problem drinkers". "The results point towards an intriguing feedback loop, where FGF21 is produced in the liver in response to sugar and alcohol intake, which then acts directly on the brain to limit consumption. We cannot rule out the possibility that beta-Klotho acts by affecting neighbouring genes, so further genetic studies are warranted," Schumann said. DNA samples were analysed from ... Scientists in the have discovered a liver hormone which plays a crucial role in controlling the drinking limits of the body.

The discovery of FGF21, reported in the 'Proceedings in the National Academy of Sciences' journal this week, could lead to a pill that could help alcoholics curb their cravings for alcohol.

Professor Gunter Schumann, from the Institute of Psychiatry at said: "Our study reveals a previously unrecognised liver-brain pathway which regulates alcohol consumption in humans, and which could one day be targeted therapeutically to suppress consumption in problem drinkers".

"The point towards an intriguing feedback loop, where FGF21 is produced in the liver in response to sugar and alcohol intake, which then acts directly on the brain to limit consumption. We cannot rule out the possibility that beta-Klotho acts by affecting neighbouring genes, so further genetic studies are warranted," Schumann said.

samples were analysed from more than 105,000 people of European descent, who were also questioned about their weekly drinking habits.

Although the effect that the gene had was small, the possible mechanism involved may lead to a target for drugs to help people to cut down on their drinking.

Co-author Professor Paul Elliott, from Imperial College London, said: "Our findings may eventually lead to new treatments for people whose health is being harmed by drinking."

By looking at the genomes of the research sample, researchers found that even moderate drinking was increased by gene mutation.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

image
Business Standard
177 22

UK scientists discover hormone to curb alcohol cravings

Scientists in the have discovered a liver hormone which plays a crucial role in controlling the drinking limits of the body.

The discovery of FGF21, reported in the 'Proceedings in the National Academy of Sciences' journal this week, could lead to a pill that could help alcoholics curb their cravings for alcohol.

Professor Gunter Schumann, from the Institute of Psychiatry at said: "Our study reveals a previously unrecognised liver-brain pathway which regulates alcohol consumption in humans, and which could one day be targeted therapeutically to suppress consumption in problem drinkers".

"The point towards an intriguing feedback loop, where FGF21 is produced in the liver in response to sugar and alcohol intake, which then acts directly on the brain to limit consumption. We cannot rule out the possibility that beta-Klotho acts by affecting neighbouring genes, so further genetic studies are warranted," Schumann said.

samples were analysed from more than 105,000 people of European descent, who were also questioned about their weekly drinking habits.

Although the effect that the gene had was small, the possible mechanism involved may lead to a target for drugs to help people to cut down on their drinking.

Co-author Professor Paul Elliott, from Imperial College London, said: "Our findings may eventually lead to new treatments for people whose health is being harmed by drinking."

By looking at the genomes of the research sample, researchers found that even moderate drinking was increased by gene mutation.

(This story has not been edited by Business Standard staff and is auto-generated from a syndicated feed.)

image
Business Standard
177 22

Upgrade To Premium Services

Welcome User

Business Standard is happy to inform you of the launch of "Business Standard Premium Services"

As a premium subscriber you get an across device unfettered access to a range of services which include:

  • Access Exclusive content - articles, features & opinion pieces
  • Weekly Industry/Genre specific newsletters - Choose multiple industries/genres
  • Access to 17 plus years of content archives
  • Set Stock price alerts for your portfolio and watch list and get them delivered to your e-mail box
  • End of day news alerts on 5 companies (via email)
  • NEW: Get seamless access to WSJ.com at a great price. No additional sign-up required.
 

Premium Services

In Partnership with

 

Dear Guest,

 

Welcome to the premium services of Business Standard brought to you courtesy FIS.
Kindly visit the Manage my subscription page to discover the benefits of this programme.

Enjoy Reading!
Team Business Standard