Monkeypox typically begins with a fever, headache, muscle aches, back-aches and exhaustion. The US Centers for Disease Control and Prevention (CDC) notes that it also causes lymph nodes to swell which is unlike smallpox. WHO has said it was important to not confuse monkeypox with chickenpox, measles, bacterial skin infections, scabies, syphilis and medication-associated allergies.
The symptoms usually last for two to four weeks. It is usually a self-limiting disease.
After the initial fever phase, skin eruptions show up. Rashes are usually concentrated on the face, palms and soles of feet. It can also affect the cornea and the genital areas. These eruptions can last for two to four weeks; they harden, become painful, and get filled up with fluid and eventually with pus. Finally, the scabs form and they fall off.