High-fat diet may lead to depression

A new study has revealed that high-fat diet might create measurable changes in the brain and causes anxiety and depression in the person.

The study experts observed that taking mice off a high-fat diet completely reversed the animals' metabolic impairments and lessened their anxious symptoms.

"This finding reinforcing the idea that the normalization of metabolic parameters may give a better chance of achieving remission, particularly in depressed patients with type 2 diabetes," said Dr. Bruno Guiard, senior author of the study.

Dr. Guiard said that when treating depression, in general there is no predictor of treatment resistance, so if we consider metabolic disorders as a putative treatment resistance predictor, this should encourage psychiatrists to put in place a personalized treatment with antidepressant drugs that do not further destabilize metabolism.

The study is published in British Journal of Pharmacology.