Thirty people were killed in the accident 50 km near Sharm el-Sheikh. The toll could increase, said Mohamed Lashin, Health Ministry Undersecretary in South Sinai.
"Still there is a number of bodies and injured people under the two buses," said Lashin.
The victims are of different nationalities, he said.
Egypt has one of the world's highest traffic accident rates due to careless driving, road and vehicle conditions which leads to death and injury of thousands every year.