Conan O'Brien, Adam Levine, Bryan Cranston, Jeff Daniels, Jon Cryer, Peter Dinklage and Dennis Farina have also been lined up for cameos in season 12, reported Digital Spy.
Kutcher's girlfriend Mila Kunis currently voices Family Guy character Meg Griffin.
Meanwhile, showrunner Steve Callaghan revealed at Comic-Con 2013 that one of the six main characters will be killed off in the new season.
"One special episode we have for the fall, we're going to kill off one of the Griffin family and replace them with a different character," he said.
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