"Krampus" director Michael Dougherty is helming the project from a script he penned with Zach Shields.
The two have joined the previosuly announced cast Millie Bobby Brown, Kyle Chandler, Vera Farmiga and O'Shea Jackson Jr, reported Variety.
Plot details are being kept under wraps.
This is the major role to date for Middleditch, who is best known for playing the hoodie-obsessed tech inventor Richard Hendricks on the popular HBO series, while Whitford is popular for his Emmy Award-winning performance as Josh Lyman on "The West Wing."
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