The cast also includes Elle Fanning, Christina Hendricks, Jena Malone and Keanu Reeves, said The Hollywood Reporter.
The Danish director's follow-up to "Only God Forgives" is described as a horror movie that follows an aspiring model, who finds herself in a terrifying predicament, with her survival hanging in the balance.
Karl Glusman, Bella Heathcote, Abbey Lee and Desmond Harrington also star in the film.
Refn and Mary Laws wrote the script for the project. The film has begun shooting in LA.