"We have elements that will allow us to show that the regime knowingly used chemical weapons," Ayrault said of the suspected chemical attack in Khan Sheikhun on April 4.
"In a few days I will be able to bring you the proof," he told French television.
In an exclusive interview last week with AFP in Damascus, Assad said the suspected chemical attack was a "fabrication" to justify a US missile strike on Syrian forces.
Western leaders including US President Donald Trump have accused Assad of being behind the attack in the rebel-held town, saying his forces used a chemical weapon during an air strike.
The suspected attack killed at least 87 people, including many children, and images of the dead and of suffering victims provoked global outrage.
The missile strike was the first direct US military action against Assad's forces since the start of Syria's civil war six years ago and precipitated a downward spiral in ties between Washington and Moscow.
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