Varadkar, officially took over as Taoiseach, as the Irish prime ministerial title is known in Ireland, after a parliamentary vote confirmed him as the leader by 57 votes to 50, with 47 abstentions.
The former general physician, who is the son of an Irish nurse and a doctor from India, won the Fine Gael party leadership earlier this month. He has made his leadership rival Simon Coveney the deputy leader of the party.
After the win, Varadkar had said, "If my election shows anything it's that prejudice has no hold in this Republic."
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