Top seed Jayaram struggled past Canada's Martin Giuffre 17-21 21-17 21-13 in a 54-minute match to set up a fight with Austria's David Obernosterer.
Second seed H S Prannoy also made it to the pre-quarters after a hard-fought 13-21 21-11 21-15 win over Sweden's Mattias Borg in another men's singles match. He will next take on B R Sankeerth of Canada.
Commonwealth Games bronze medallist, RMV Gurusaidutt also stormed into the next round after an easy 21-8 21-6 win over local shuttler Jonathan Lai and will now face eighth seed Raul Must of Estonia next.
Young shuttler Pratul Joshi also registered a 21-13 21-12 win over Scotland's Alistair Casey and his next match will be against fellow Indian Harsheel Dani.
In women's singles, 2015 National Champion Ruthvika Shivani Gadde defeated local player Kyleigh O' Donoghue 21-14 21-14. She will next face Austria's Elisabeth Baldauf.
Runners-up at 2016 Senior National championship, Tanvi Lad also made it to the prequarterfinals after defeating Denmark's Julie Finne-Ipsen 21-17 21-10 and will face Maya Chen of USA next.
Rio-bound Indian men's doubles pair of Manu Attri and B Sumeeth Reddy, top seeded, will face Canadian combo of Timothy Chiu and Jason Ho-Shue.
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