Brad Anderson, who directed 'The Call', is directing the movie, which is loosely based on one of Edgar Allan Poe's early works 'The System of Doctor Tarr and Professor Fether', said the Hollywood Reporter.
Beckinsale, 39, will play the title character of Eliza, a patient at a mental institution in which the inmates have taken over and are posing as doctors.
She becomes the object of affection of a newly arrived Harvard Medical School grad who has no idea of the topsy-turvy world he just entered.
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