Emergency services were summoned to Long Meadow Walk, Lowestoft, to find a red Audi TT had left the road and crashed into the home.
A man was removed from the car and taken to the James Paget Hospital with serious head injuries, the BBC reported.
He has since been transferred to Addenbrooke's Hospital.
Structural engineers are on site to inspect the property. No-one inside the house was injured, the report said.
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