Ranked 313, Myneni upset the local favourite and top seed 6-4 4-6 7-5 in one hour and 55 minutes.
Second seed Somdev, ranked 91, had to fight it out with 192 ranked Australian as he came from behind for a 3-6 6-3 6-4 win in the first round of the USD 75,000 hard court tournament.
It took Somdev, who is known for playing long matches, almost two hours to beat his opponent.
Somdev is to compete in the doubles event as well with compatriot Sanam Singh. They will take on American wild cards Mitchell Frank and Mac Styslinger in their first round.
