A spokesman for the Spanish star tweeted: "RafaelNadal felt earlier today and didn't finish the practice. It looks like his ankle is OK however we will see how things evolve."
Second seed Nadal, a four-time Miami runner-up, is coming off a run to the quarter-finals at Indian Wells, where he lost to Canada's Milos Raonic.
World number three Nadal will have a first-round bye in this week's start to the Masters Series event and open against the winner between Ukraine's Sergiy Stakhovsky and Spain's Nicolas Almagro, with ninth-ranked Czech Tomas Berdych a potential quarter-final foe.
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