The passenger double cabin van, travelling from Parachinar to Piwar Tangi area of Upper Kurram Agency, was hit by a road side Improvised Explosive Device (IED) near the Pak-Afghan border area, officials said.
One person was killed while two others injured in the blast, they said.
Separately, at least two security force personnel were injured when a roadside IED targeted their vehicle in Peshawar's Wazir Bagh area. The vehicle was completely damaged.
Meanwhile, residents of Parachinar held a protest demonstration here against the twin blasts which ripped through a congested market and a taxi stand in the city on Friday.