The study, led by Dr Carl Hulston based in the Loughborough University's School of Sport, Exercise and Health Sciences, suggests that the composition of the gut microbiota is an important factor in understanding metabolic disease in humans.
For the study, seventeen healthy individuals were split into two groups. Both maintained their habitual food intake for the first three weeks of the study.
One of the groups also consumed two bottles of a probiotic fermented milk drink every day.
The main finding of the study was that high-fat overfeeding for seven days decreased insulin sensitivity by approximately 27 per cent within these healthy volunteers. But the group that consumed the probiotic drink preserved their glycaemic control and maintained insulin action.
The results provide further indirect evidence that changes in the gut microbiota are involved in the development of human metabolic disease and, furthermore, that supplementation with a probiotic could help prevent insulin resistance caused by excessive consumption of high-fat foods.
"Therefore the demonstration by this study that a probiotic has the potential to prevent insulin resistance in humans is a significant breakthrough. This warrants further investigation on a larger scale to support our initial findings," Hulston added.
The study was published in the British Journal of Nutrition.
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