The film titled, "Bohemian Rhapsody", stars Rami Malek as the legendary singer and shooting was underway in London, according to BBC.
"Twentieth Century Fox Film has temporarily halted production on 'Bohemian Rhapsody' due to the unexpected unavailability of Bryan Singer," the studio said in statement.
"This is a personal health matter concerning Bryan and his family. Bryan hopes to get back to work on the film soon after the holidays," it added.
According to reports, it is not the first time that Singer has taken a break. He had vanished from the sets while shooting "X-Men: Apocalypse" and "Superman Returns".
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