The villagers were travelling from Pacheer Agam district to a nearby village in Nangarhar province, Hijratullah Rahmani district governor of Pacheer Agam told AFP.
"Unfortunately, in the blast, seven civilians, including a woman and three children were killed and one wounded," he said.
No one claimed responsibility, but the interior ministry in a statement blamed "enemies of peace and stability," a term Afghan officials use to refer to Taliban.
Nangarhar is also home to Islamic State group fighters, who are trying to expand their presence in Afghanistan by winning over sympathizers, recruiting followers and challenging the Taliban on their own turf.
Last week, over 50 people, mostly civilians, were killed in multiple Taliban bombings across Afghanistan.
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