The 42-year-old actress will recur on the "Walking Dead" spin-off as a "confident and skilled" doctor named Bethany Exner, Deadline reported.
Holt is known for starring in the US remake of "The Returned", and played Gillian Cole in "House of Cards".
"Fear the Walking Dead" takes place in Los Angeles at the very beginning of the zombie apocalypse.
Kim Dickens, Cliff Curtis, Frank Dillane, Alycia Debnam-Carey, Elizabeth Rodriguez and Mercedes Mason will be among a new crop of survivors.
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