"I do worry. I think everyone should worry. We need to look after them [animals], because otherwise our children will not have a chance to see what we have seen," Harry said.
"This is God's test: If we can't save some animals in a wilderness area, what else can't we do," the 32-year-old prince told US magazine'Town & Country'.
Britain's fifth in line to the throne had spoken to the magazine while he was working on a conservation project in Malawi last year.
"I do believe we need a regulatory body so that everyone who owns or manages wildlife is subject to inspection and rated on how well they look after the animals and how the communities benefit. We have to come together," he said.
On a personal note, he recalled how he had first visited Africa after his mother Princess Diana died in 1997.
"I first came in 1997, straight after my mum died. My dad told my brother and me to pack our bags - we were going to Africa to get away from it all. This is where I feel more like myself than anywhere else in the world. I wish I could spend more time in Africa. I have this intense sense of complete relaxation and normality here.
The magazine has him on the cover posing in a dark green shirt under the headline "Bachelors of the year".
During his time in Africa last year, the royal had helped catch anaesthetised elephants and load them on trucks which moved them 200 miles from Liwonde National Park and Majete Wildlife Reserve to the Nkhotakota reserve, where the elephants can thrive.
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