The 30-share barometer, which had lost 161.49 points in the previous session, fell by 55.22 points, or 0.19 per cent, to 28,282.83 with stocks of realty, banking, auto, IT, metal and capital goods sectors declining the most.
Also, the National Stock Exchange index Nifty was down by 18.70 points, or 0.22 per cent, to 8,444.40.
Brokers said apart from profit-booking in recent gainers, trimming of positions by speculators in view of tomorrow's monthly expiry in the derivatives segment, influenced sentiments.
Among other Asian markets, Hong Kong's Hang Seng was trading 0.21 per cent higher, while Japan's Nikkei fell 0.07 per cent in early trade.
The US Dow Jones Industrial Average ended 0.02 per cent lower in yesterday's trade.
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