Twenty-two suspects were arrested in the eastern province of Erzurum including alleged senior members of the jihadist group, and 39 suspects in the northwestern Bursa province, the official Anadolu news agency reported, citing security sources.
The suspects included two Azerbaijanis and 28 Syrians, it added.
The operation comes a day after police arrested 49 alleged IS members in Ankara -- some of whom were suspected of planning an attack on Republic Day on Sunday.
There has been a lull in attacks since, but tensions remain high and Turkish police launch raids almost daily against suspected IS cells across the country.
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