Sergeant Debra Clayton, a mother of two, was fatally shot early Monday morning, Orlando Police Chief John Mina told journalists.
A 17-year-veteran of the department, Clayton had been attempting to arrest a suspect in the murder of a pregnant woman when he gunned her down.
While searching for the gunman an Orange County deputy sheriff riding his motorcycle was struck by a vehicle that turned in front of him.
He was taken to a nearby hospital and died of his injuries, according to Orange County Sheriff Jerry Demings.
Several schools in the vicinity of the ongoing manhunt remained on lockdown.
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