Rafael Foley was speaking at a closed meeting of the Organization for the Prohibition of Chemical Weapons' Executive Council, which was called to discuss recent reports by a fact-finding mission, including that a "non-state actor" likely used the chemical agent sulfur mustard in August during fighting in the Syrian town of Marea, killing a baby.
Foley said Syrian opposition forces were fighting the Islamic State group in the town close to the Turkish border. The text of his speech was posted on The Hague-based watchdog's website.
After the meeting, attended by representatives of 38 member states, the executive council issued a statement "expressing grave concern" about the fact-finding mission's conclusions that "chemical weapons have once again been used in" Syria and saying that those responsible should be held accountable.
A special investigation team has been set up by the United Nations and OPCW to identify who is responsible for chemical attacks in Syria.
French Prime Minister Manuel Valls warned last week that associates of extremists responsible for the November 13 Paris attacks could use chemical and biological weapons.
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