Rayan Mashaal, also known as Baraa Kadek, was reportedly killed in coalition bombardment on the IS-held town of Mayadeen, near Syria's border with Iraq, on Monday.
Several Syrian activist Facebook pages, including the prominent media collective Eye on the Homeland, shared the news of his death.
"Mashaal was one of the founders of Daesh's Amaq news agency," Eye on the Homeland said, using the Arabic acronym for IS.
"He and his daughter were killed in a coalition air strike on Mayadeen in Deir Ezzor province," the collective wrote.
Neither the US-led coalition nor the Syrian Observatory for Human Rights monitoring group could immediately confirm the news.
Mohammad Khaled, the executive director of opposition news network Aleppo24, told AFP that Mashaal, 31, had been a well-known media activist before joining IS.
"I met him in 2012. Baraa (Mashaal) was one of the old revolutionaries of Aleppo," he said.
According to Khaled, Mashaal worked as a media activist in Aleppo until late 2013, when he announced he was moving to "the land of the caliphate" in IS-held Al-Bab.
"We knew that he was founding this (Amaq) agency in 2014 because he invited all the activists in Aleppo to join him," Khaled said.
Amaq is IS's self-styled news outlet.
Its channels on social media application Telegram are often the first place that IS publishes its claims of responsibility for attacks around the world.
The US-led coalition has been bombing IS targets in Syria since September 2014 and has been heavily bombing Mayadeen since last week.
More than 320,000 people have been killed and millions displaced by Syria's conflict, which erupted in March 2011 with protests against Syrian President Bashar al-Assad.
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