Davis has been having a good run at the awards season for playing conflicted homemaker Rose Maxson in the 1950s-era drama "Fences", which has been adapted from August Wilson's Pulitzer Prize winning play.
Davis, who also won a Tony Award for playing the role on Broadway in 2010, noted its improbable path to the multiplex.
"It's not every day Hollywood thinks of translating a play to the screen," she said as she accepted her first Globe after four previous nominations. "It doesn't scream moneymaker, but it does scream art, it does scream heart."
Thanking the actor, Davis said, "Denzel, I am a friend and a fan. Thank you for being an extraordinary leader and a great actor and director. Thank you for saying trust me and remember the love."
Davis, 51, gave a special shout-out to her husband and daughter calling them "loves of her life".
Paying a tribute to her father, Dan Davis, who raised her and siblings in poverty, largely in Rhode Island, the actress called him her "Troy".
"To the original Troy, my father Dan Davis, born in 1936. He had a fifth-grade education and didn't know how to read until he was 15. But you know what? He had a story and it deserved to be told - and August Wilson told it.
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