The bomb was planted in a car parked on the Sirki road in the suburban of provincial capital Quetta.
Police official Shaukat Jadoon said that the remote controlled bomb exploded when a police mobile security vehicle was passing by, causing minor damage.
He said one person was killed and 10 injured in the attack who were shifted to a hospital.
The injured also include some school children who were in van which was also passing through the road at the time of explosion.
In a separate incident, a principal of a private school was gunned down by unknown attackers in Gwadar area of the province.
A local police official said that the motive of killing was not known. The attackers fled after the incident.
The law and order situation in the province is not good and a few days ago provincial education adviser escaped an attempt on life.
Most of the attacks are carried out by the Baloch nationalists who claim that the mineral-rich province was kept impoverished by the federal government which is exploiting the wealth of the region.
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