The infant, suffering from cardiac disease, was later declared dead by the doctor who examined him at the parking bay after the aircraft made an emergency landing.
The infant had three holes in the heart and was being taken to Chennai for a surgery, an IndiGo airline statement said here.
"IndiGo flight 6E-431 to Chennai departed on time from Mumbai and was air-borne by 10:31 AM. However, the flight had to return to Mumbai due to a medical emergency on board involving a 7-month-old infant," the statement said.
On arrival, the infant was immediately attended by a doctor, who declared him dead, IndiGo said.
"We understand the sensitivity of such situations; hence our crew on-board ensured that the infant received all possible medical attention on board and from our on-ground staff," it added.
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