World No. 2 Saina, who came into the match with a 6-3 head-to-head record, lost 9-21 15-21 to Intanon, ranked 7th, in a women's singles match that lasted 39 minutes at the Stade Pierre de Coube.
In the prequarterfinals match, Saina had tamed Japanese Minatsu Mitani in straight games after two successive defeats against the Japanese at Japan Open and Denmark Open.
Among others, H S Prannoy, Ajay Jayaram, and women's doubles pair of Jwala Gutta and Ashwini Ponnappa lost in the second round yesterday.
In men's singles, NG Ka Long Angus of Hong Kong ended the run of Prannoy, who had beaten two-time Olympic champion Lin Dan of China, with a 21-15 21-10 win in the second round.
Two-time Dutch Open winner Jayaram too failed to cross the second round after suffering a 18-21 8-21 loss to Tian Houwei of China.
2010 Commonwealth Games champions Jwala and Ashwini lost 15-21 18-21 to eight seeds Eefje Muskens and Selena Piek of Netherlands.
