The lorry was on its way from Kozhikode to Kochi when the mishap occurred around 8.30 am as the driver lost control of the vehicle while negotiating a sharp curve about five km from Vattappara, police said.
The driver sustained minor injuries, they said.
Police, fire and rescue services and IOC personnel are at the spot.
Traffic on the stretch between Valanchery and Kottakkal was diverted through Kanjipura-Moodal bypass, following the accident.
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