The three coaches of the Dimapur-Kamakhya train jumped the tracks but toppled down near Jagiroad in Morigaon district at 0205 am, they said.
Seventeen passengers were seriously injured and shifted to Gauhati Medical College Hospital, police said.
Rest of the passengers were reported to have received minor injuries and were released after receiving first aid in Morigaon Civil Hospital, Northeast Frontier Railway sources said.
Senior railway officials have rushed to the site and rescue operations are on.
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