Gene Editing

Preventive, a San Francisco startup backed by OpenAI's Sam Altman and Coinbase's Brian Armstrong, is researching embryo gene editing to prevent hereditary diseases

Scientists find that SDR42E1 gene, vital for vitamin D use, could be targeted to treat cancers and immune disorders without harming healthy cells

Lilly has struck multiple partnership deals with gene-editing companies in the last two years to expand its portfolio beyond its blockbuster weight-loss and diabetes drugs

Indian-origin cardiologist Kiran Musunuru leads breakthrough CRISPR gene editing therapy for rare genetic disorder focusing on heart disease genetics and new treatments

A nine-month-old with a fatal liver condition became the first to receive a CRISPR-based DNA-editing therapy custom-built to repair his unique mutation

Scientists used CRISPR-Cas9, a precision gene-editing technique, to create a variety of risotto rice potentially resistant to Pyricularia oryzae, a pathogenic fungus which leads to rice blast disease

The agency approved Lyfgenia from bluebird bio, and a separate treatment called Casgevy by partners Vertex Pharmaceuticals and Crispr Therapeutics

The unique characteristics of wastewater, which allow resistance genes to grow against harmless bacteria to those that cause disease, provide a potent breeding ground for antibiotic resistance to evolve, according to a new study. Researchers at the Centre for Antibiotic Resistance Research (CARe) in Gothenburg, Sweden, presented evidence for where the genes could gain their ability to move in a study published in the journal Communications Biology. It is not enough for the antibiotics alone to drive the process, they acknowledged. For the movement of reistant genes, the species carrying the resistance genes in their chromosomes need to be present, along with the specific DNA sequences providing for their movement. The researchers analysed DNA from thousands of samples across different environments and found that all these key components came together not in the gut of humans or animals, but in wastewaters. "In order to fight antibiotic resistance we cannot focus only on preventing

The endogenous manufacturing of CRISPR components, through greater research, would make India a commercially successful country in the field of Deep Science, according to Girish Krishnamurthy, CEO & MD, Tata Medical and Diagnostics Ltd.Participating in a panel discussion on 'Gene-Editing On Centre Stage' at the 'Bengaluru Tech Summit 2021', Krishnamurthy opined that the therapeutics R & D is slow in India as compared to the West, hence seeking deeper research experiences is significant."The country also needs to address associated infrastructural issues like the building of cold storage, expanding supply chains and the sorts," he said.The CEO also highlighted the misconception amongst people that CRISPR is meant for therapeutic and not diagnostic purposes and that it needs to change. With basic technology and market being the most crucial focal points, a large number of its applications are to be looked at, serving both urban and rural India.Though grants are channelized ...

Aedes aegypti is a salt-and-pepper scourge on humans worldwide

Research provides insights into the molecular pathways involved in accelerated ageing.

Many scientists and researchers claimed that the report of the genetically-edited babies was 'unverified,' but said that if true it would be 'monstrous'

If the ancients knew that they could interfere with the genetic code, the bag of worms, would they have done that? And should we do it today?

Here are answers to some of the numerous questions swirling around this development

The experiment, led by Chinese scientist He Jiankui, claims to have altered the DNA of twin girls born a few weeks ago to prevent them from contracting HIV.

A hospital linked to Chinese scientist's gene-editing research suggested its ethical approval had been forged.

Various bodies have emphasized that, for gene editing to proceed to human trials, a robust public discussion is first needed to establish its legitimacy

He Jiankui, an American-educated scientist based in Shenzhen, announced on Monday that he'd used Crispr, a powerful gene-editing tool, to make recently born twin girls resistant to HIV

There is no independent confirmation of He's claim, and it has not been published in a journal, where it would be vetted by other experts

Gene-editing could mean bigger harvests of crops with a wide array of desirable traits - better-tasting tomatoes, low-gluten wheat