PSV Eindhoven started off their Champions League by defeating Manchester United 2-1 in the opening match at Philips Stadion on Tuesday.
United's Memphis Depay, who returned to the club where he made his name, scored an opening goal for his side in 41st minute, Sport24 reported.
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But just four minute after United's goal, central defender Hector Moreno'goal leveled the score.
PSV winger Luciano Narsingh doubled the lead in 57th minute to claim their first victory.
United will now lock horns with Wolfsburg on October 1.