Excluding asset sales net profits at the world's largest pharmaceutical company by sales fell by 5 per cent to USD 12 billion, missing expectations of analysts polled by the Swiss financial news agency AWP of an average of USD 12.1 billion.
Last year, the company finalised a series of transactions with GlaxoSmithKline, Eli Lily and CSL to offload its vaccine, animal health and consumer health products businesses.
Net sales also slid 5 percent to USD 49.4 billion but when currency changes were stripped out that represents a 5 per cent gain, the company said.
"In 2015, we completed our portfolio transformation, delivered solid financial results and improved core margin despite a very strong currency impact," chief executive Joseph Jimenez said in a statement.
Core operating income margin climbed 1.3 percentage points in constant currency terms.
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