Both campaigners were reacting to leaked IAAF files containing suspicious blood tests among 12,000 samples involving 5,000 athletes, reported on by German broadcaster ARD and British newspaper The Sunday Times. They allege the IAAF did not act on them.
Bubka did not directly address the allegations in a statement on Wednesday, but claimed a "more proactive" approach against cheating was needed.
"At present, the anti-doping system is too complex and takes too long," Bubka said. "It needs to be simplified to become faster and more efficient, and we need to deploy the best research and science to ensure that we keep a step ahead of the dopers.
Bubka, the pole vault great from Ukraine, is standing against Coe to replace outgoing president Lamine Diack at an election in Beijing in two weeks.
On Tuesday, Coe, like Bubka a vice-president at the IAAF, decried the media reports, calling them misinformed and unwarranted, and "a declaration of war on my sport.
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