In a photo, the 49-year-old actor is seen posing with the first responders. He is on the mend, reported People magazine.
"Charlie was hospitalised for severe case of food poisoning. It was clams, bad clams. Nothing too exciting," his publicist said.
Sheen had a seafood dinner delivered to his house and began "feeling sick" a few hours later.
"Just to be on the safe side, he went to the hospital. They checked him out, hydrated him and sent him on his way. He was back home in bed 90 minutes later," the publicist added.