De Villiers, who turns 33 next month, said his main goal for the rest of his career was to lead South Africa at the 2019 Cricket World Cup in England.
"We haven't won a World Cup yet," said De Villiers, who is captain of the South African one-day team. "For me, for now the most important thing is the 2019 World Cup. I want to make sure we get there. I want to make sure we lift that trophy. I feel that if I play all formats all the time, then mentally and physically I won't be at my best."
De Villiers is recovering from a long-term elbow injury which has kept him out of action since July.
He is due to make a low-key comeback in a one-day match for the Northerns provincial team on Sunday.
But he said he had recovered fully and would play in the third of three Twenty20 internationals against Sri Lanka in Cape Town on January 25 before captaining South Africa in a five-match one-day series against the Sri Lankans.
Haroon Lorgat, chief executive of Cricket South Africa, said he hoped De Villiers would be available for four Test matches in England starting in July.
"I've been engaged with him for some time and we've given him the latitude of taking time off and setting himself for the 2019 World Cup," said Lorgat.
"We're taking it one series at a time. I'm confident that by the time we get towards looking at England and the Champions Trophy (in June), he'll be fully fit and raring to go. His appetite would have returned because then it would be a fair amount of time he has had. I'm confident England is a kind of series that he would want to be available for."
But after his injury kept him out of series against New Zealand, Australia and Sri Lanka, he gave up the Test captaincy in favour of former schoolmate Faf du Plessis.
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